Definition of Reuptake

Reuptake:This term refers to the process by which a cell reabsorbs a substance that it initially secreted. This mechanism can significantly influence various bodily functions. For instance, serotonin, a neurotransmitter produced by brain cells, is used by nerves to communicate. When a nerve cell releases serotonin, it enters the surrounding space and can either bind to receptors on nearby nerve cells or attach to receptors on the original nerve cell, where it is reabsorbed, recycled, and released again. This cycle is known as reuptake. Typically, serotonin maintains a balance between attaching to neighboring nerves and being reabsorbed. Certain medications, known as reuptake inhibitors, prevent serotonin from being reabsorbed, thereby altering its levels in the brain. The term "reuptake" can also be spelled "re-uptake."

Medical Definition & Meaning