Definition of Rh factor

Rh factor: This is an antigen present on the surface of red blood cells. If red blood cells possess this antigen, they are categorized as Rh positive (Rh+). Conversely, those lacking the antigen are classified as Rh negative (Rh-). For blood transfusions, it's crucial to ensure that the donor's Rh status matches the recipient's, in addition to the ABO blood type, because Rh- individuals can develop complications if they receive Rh+ blood. Rh typing is also vital in situations such as miscarriage, pregnancy, and childbirth, due to potential Rh incompatibility between the mother and the fetus. The term "Rh" derives from rhesus monkeys, where this antigen was initially discovered. For further information, refer to Rh incompatibility.

Medical Definition & Meaning