Definition of Paleostriatum

Paleostriatum:This term refers to a pale-looking, rounded region in the brain. It is specifically a portion of the lentiform nucleus, which is itself part of the striate body—a significant collection of gray matter located at the base of the cerebral hemispheres. The cells within the paleostriatum can be particularly vulnerable to damage and death due to carbon monoxide poisoning, barbiturate overdose, hydrogen sulfide poisoning, or prolonged severe conditions, and it is also affected in Wilson disease. The name "paleostriatum" translates to "old stratum," as it was believed to have developed before the neostriatum (or new stratum), another part of the brain's striate body. The paleostriatum is also known as the globus pallidus, with "globus" meaning "globe" in Latin and "pallidus" referring to its pale appearance.

Medical Definition & Meaning