Lipodystrophy is a condition affecting fatty tissue, marked by the specific loss of body fat. Individuals with this disorder often develop insulin resistance, elevated triglyceride levels (known as hypertriglyceridemia), and fatty liver. Lipodystrophy can be classified into several types, either hereditary (genetic) or non-hereditary (acquired). The hereditary forms include generalized lipodystrophy (also known as Berardinelli-Seip syndrome) and various forms of partial lipodystrophy, such as the Dunnigan type, Kobberling type, and mandibuloacral type. The acquired versions encompass acquired generalized lipodystrophy (referred to as Lawrence syndrome), acquired partial lipodystrophy (Barraquer-Simons syndrome), and lipodystrophy resulting from inhibitors used in certain treatments.
