Definition of Immune thrombocytopenic purpura

Immune thrombocytopenic purpura (ITP) is a condition where blood platelets are destroyed due to the presence of autoantibodies targeting the patient's own platelets. This disorder leads to a reduction in the number of platelets, also called thrombocytes. It is often marked by the appearance of purplish spots on the skin and mucous membranes, such as the lining of the mouth, caused by bleeding due to low platelet levels. ITP can be induced by medications or linked to infections, pregnancy, or immune system disorders. In approximately half of the cases, the cause remains unidentified, which is referred to as "idiopathic." The term "ITP" is commonly used to denote both immune thrombocytopenic purpura and idiopathic thrombocytopenic purpura.

Medical Definition & Meaning