Hereditary angioedema, also known as Quinke's disease, is a genetic condition that occurs when individuals are born without an essential protein called C1 esterase inhibitor. This protein normally stops a series of reactions that lead to the tissue swelling characteristic of angioedema. Those affected can experience episodes of tissue swelling, abdominal pain, and airway swelling, which may obstruct breathing. The condition is usually suspected in individuals with a history of repeated angioedema episodes and is confirmed by detecting unusually low levels of C1 esterase inhibitor in the blood. Treatment methods include the administration of androgens, a type of male steroid, which help prevent recurring attacks. This condition is also referred to as hereditary angioneurotic edema.

CPR Certification Labs provides hands-on, American Heart Association–aligned CPR, BLS, ACLS, and PALS certification training to help providers master these life-saving skills.