Cystic Fibrosis (CF) is among the most prevalent and severe genetic disorders, impacting the glands and leading to the production of unusual secretions. This results in mucus accumulation, which can hinder the pancreas and, subsequently, the intestine. Over time, this mucus build-up can significantly impair lung function. Without intervention, 95% of children with CF do not survive past the age of five. Nevertheless, with comprehensive medical care, individuals with CF are now living well into middle age.Early detection of CF is crucial, as initiating and maintaining treatment is essential for prolonged survival. As the life expectancy of individuals with CF increases, new issues have arisen. For instance, among 75 adult women with CF, 68% experienced urinary leakage in the past year, triggered by actions such as coughing, sneezing, or laughing, and it was more severe when their respiratory condition worsened.CF is inherited in an autosomal recessive pattern and affects both genders equally. Among white couples, one in 400 is at risk of having a child with CF, with a 1 in 4 chance per pregnancy. This makes the overall risk for their child to have CF 1 in 1600. If a couple already has a child with CF, each subsequent child has a 25% risk of being affected.The management of CF involves therapies to clear lung mucus, the use of pancreatic enzymes, and medications to combat severe lung infections. CF is caused by mutations in the CFTR gene, located on chromosome 7.Citrovorum factor.
