Factor X, a crucial component in blood, plays an essential role in the normal clotting process. It is produced in the liver and requires specific conditions for its synthesis. The gene responsible for factor X is located on chromosome 13, specifically at band 13q34. The "X" in factor X represents the Roman numeral "ten," as all coagulation factors are denoted by Roman numerals. Factor X gained recognition due to a genetic disorder characterized by its deficiency.This deficiency is inherited and leads to symptoms such as prolonged nosebleeds, excessive menstrual bleeding, bruising, and hemarthrosis (bleeding into the joints). Women with factor X deficiency often face challenges during pregnancy, including increased risks of miscarriage, placental abruption, and premature birth. Factor X is also known as the Stuart-Prower factor, named after Mr. Stuart and Miss Prower, the first individuals identified with this deficiency.
